中药药剂学研究前沿:组分制剂技术基础与关键科学问题

Research frontiers of Chinese medicine pharmaceutics:foundations and key issues of components preparation technology

组分制剂在遵循中药整体性和系统性的基础上,将中药多成分的复杂问题简易化,为中药制剂的发展提供了一种有效的、可行的模式,已成为中药制剂研究的热点,也被认为是实现中药现代化的有效途径之一。本文在既往组分相关研究的基础上,结合本课题组的研究工作,重点针对组分性质及其表征技术、组分释药单元的构建及多元释药系统等方面阐述组分的研究前沿,探讨组分制剂技术基础与关键问题,为相关研究者带来一定的启发及思考。

Based on the integrity and systematicness of Chinese medicine,the components preparation simplifies the complex problems of multi-components of Chinese medicine,provides an effective and feasible model for the development of Chinese medicine preparation.It has become a hot topic in the research of preparation,and is also considered as one of the effective ways to realize the modernization of Chinese medicine. Based on the previous research on multi-components and the work of our research group,the research frontiers of multi-components are elucidated,including the properties and characterization techniques of components,the construction of components release unit,and the multiple drug delivery system.The purpose of this paper is to explore the technical basis and key problem of components preparation,and then bring some inspiration and thought to the relevant researchers.