冠状动脉粥样硬化性心脏病血运重建术后患者门诊二级预防用药调查

Secondary prevention in outpatients after revascularization of coronary atherosclerotic heart disease

目的调查冠状动脉粥样硬化性心脏病(冠心病)血运重建术后患者门诊二级预防药物使用情况。方法回顾性分析2015年5-12月于首都医科大学附属北京安贞医院就诊的血运重建术后冠心病患者676例病历资料。收集患者性别、年龄、是否医保、合并症(高血压、糖尿病)、血运重建方式(经皮冠状动脉介入、冠状动脉旁路移植术、经皮冠状动脉介入+冠状动脉旁路移植术)等基本资料,分析患者二级预防药物服用情况及影响因素。结果本研究纳入的676例血运重建术后患者阿司匹林、氯吡格雷/替格瑞洛、他汀类药物、β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗剂服用率分别为98.1%(663例)、96.0%(649例)、99. 1%(670例)、97.8%(661例)、96. 2%(650例)。阿司匹林、氯吡格雷/替格瑞洛、他汀类药物、β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗剂药物服用率与性别、年龄、是否医保、是否合并高血压、是否合并糖尿病和血运重建方式均无明显相关性(均P>0.05)。结论北京安贞医院血运重建术后冠心病患者门诊二级预防药物服用率较高,患者性别、年龄、是否医保、是否合并高血压、是否合并糖尿病和血运重建方式对二级预防药物服用率均无明显影响。

Objective To investigate the use of secondary prophylactic drugs in outpatients of coronary atherosclerotic heart disease(CHD)after revascalarization.Methods Clinical data of 676CHD patients underwent revascularization in Beijing Anzhen Hospital,Capital Medical University from May to December 2015were retrospectively analyzed.Basic information (sex and age),medical insurance,complications (hypertension and diabetes),revascularization methods(percutaneous coronary intervention and coronary artery bypass grafting)and secondary prophylactic medication were analyzed.Results Use rates of aspirin,clopidogreL/ticagrelor,statins, [3-blockers and angiotensin converting enzyme inhibitor/angiotensin 1]receptor blocker(ACEI/ARB)were 98.1% (n =663),96.0*7o (n =649),99.1%(n =670),97.8%(n =661)and 96.2%(n =650),respectively.There was no significant relation of drug use with sex,age,medical insurance,hypertension,diabetes and revaseularization methods(all P >0.05).Conclusions Use rate of secondary prevention drugs in CHD patients after revascularization is high.Sex,age,medical insurance,hypertension,diabetes and revaseularization methods show no significant influence on the drug use.