南通市流感病毒监测结果质量评价探讨

Quality evaluation of influenza virus monitoring results in Nantong

目的分析南通市流感病毒监测结果,找出存在问题,提高流感监测水平。方法对南通市1个流感自然监测年期间采集的咽拭子样品病毒核酸监测结果进行分析。结果 2015年由哨点医院采集的ILI咽拭子标本流感病毒核酸阳性率为8. 90%(282/3 168),病毒亚型以季节性H3为主,暴发疫情报告2起,病毒亚型为乙型Victoria流感型和季节性H3型, 2015年流行高峰月在秋冬季与夏季。结论南通市流感监测系统总体运行正常,病毒核酸阳性标本的检出率与样品采集、送检、保存、实验室检测等多因素相关,建议加强专业人员培训和技术指导,提高工作技能,聚集性疫情的监测存在局限性,应加大媒体相关知识宣传,增强公众疫情敏感性,将病例监测和病原学监测有效结合,有利于提高流感监测质量。

Objective To analyze the monitoring results of influenza virus in Nantong city,identify the problems,and increase the level of influenza monitoring. Methods To analyze the viral nucleic acid monitoring results of throat swab samples collected during a natural influenza monitoring year in Nantong city. Results In 2015,the positive rate of influenza virus nucleic acid of ILI throat swab specimens collected by sentinel hospitals was 8. 90%( 282/3 168). The virus subtypes was mainly seasonal H3 virus. Outbreak occurred twice,the virus subtypes were influenza B Victoria viruses and seasonal H3 viruses,autumn,winter and summer were the peaks in 2015. Conclusion The influenza monitoring system of Nantong city is generally operating normally. The detection rate of positive viral nucleic acids is related to many factors,such as sample collection,submission,preservation,and laboratory testing. It is recommended that professional training and technical guidance be strengthened to improve job skills; there are limitations in the monitoring of aggregated outbreaks,and more media related knowledge should be publicized to increase the sensitivity of public outbreaks. Effective integration of case monitoring and etiological monitoring will help to improve the quality of influenza monitoring.