固相微萃取在苯丙胺类毒品分析中的应用

Application of solid phase microextraction in the analysis of amphetamine-type drugs in the biological samples

固相微萃取(solid phase microextraction, SPME)作为一种新型样品前处理技术已受到广泛关注。由于SPME集采样、萃取、浓缩、进样于一体,克服了传统样品前处理技术步骤繁琐、耗时耗力、所需样品量大等诸多缺点,因此在对生物样品中毒品等目标物的分析中具有巨大的应用潜力。本文以纤维SPME技术为例,综述了该技术在苯丙胺类毒品分析中的研究进展,并对其发展方向进行了展望。

As a new sample pretreatment technique,solid-phase microextraction (SPME)has attracted a lot of attention.SPME integrates sampling,extraction,concentration and injection into a single step and overcomes some drawbacks those conventional pretreatment techniques possess,such as being tedious,time-consuming and requiring large amounts of samples,etc.Therefore,SPME has great application potential in the drug analysis in the biological samples.Based on fiber-SPME,the application of SPME in the analysis of amphetamines in the biological samples is summarized and the further development directions are suggested.