上呼吸道感染对眩晕患儿前庭功能影响的相关性研究

Effect of upper respiratory tract infection on vestibular function in children with vertigo

目的研究上呼吸道感染对眩晕患儿前庭功能的影响,明确感染导致的前庭受损部位,为进一步治疗提供依据。方法采用病例对照研究方法,2016年3月～2018年2月门诊就诊的眩晕患儿,明确2周内上呼吸道感染病史41例,同期门诊就诊非感染眩晕患儿40例纳为对照组。观察两组的冷热试验、颈肌前庭诱发肌源性电位及眼肌前庭诱发肌源性电位结果并进行比较分析。感染组内根据病原学种类、病史长短及眩晕程度不同进行亚组比较。结果感染组前庭功能异常率高于对照组(χ2=6.522,P=0.011)。感染组内病原学种类、眩晕程度及病程长短对于前庭功能异常的影响没有统计学意义(P>0.05)。上呼吸道感染累及前庭上神经及全前庭神经者均高于前庭下神经。结论上呼吸道感染影响眩晕患儿的前庭功能,与病原体种类、病史长短及眩晕程度无关。

OBJECTIVE To evaluate the effect of upper respiratory tract infection on vestibular function of children with vertigo,and identify the vestibular lesions for further treatment.METHODS The children with vertigo who were treated in the outpatient clinic from March 2016 to February 2018 were included.The infected group included 41 vertigo patients with a history of upper respiratory tract infection within 2 weeks,and control group included 40 vertigo patients with non-infected at the same period. Vestibular system was assessed using caloric test,cervical vestibular evoked myogenic potential and ocular vestibular evoked myogenic potential.RESULTS The abnormal rate of vestibular function in the infected group was higher than that in the control group(P=0.011).It was also showed that there was no statistically difference between abnormal vestibular function and pathogen type,degree of dizziness and length of history(P>0.05).The superior vestibular nerve and the whole vestibular nerve were infected easier than the inferior vestibular nerve.CONCLUSION Abnormal vestibular function in children with vertigo was affected by upper respiratory tract infection,which was not associated with the pathogenic type,the length of history and the degree of vertigo.