上海市松江区某社区成年人慢性肾病流行现况调查

Epidemiological features of adult chronic kidney diseases in a community-based population in Songjiang district,Shanghai

目的了解上海市松江区某社区成年人慢性肾病(chronickidney disease,cKD)的流行现况及主要相关因素。方法采用随机整群抽样的方法抽取上海市松江区新桥镇20—75岁的常住居民9257名进行CKD及其相关因素的问卷调查、体格检查及血尿常规、生化检测。结果本次调查资料完整的对象共8207名,经年龄和性别调整后,调查人群CKD患病率为8.4%(95%CI:7.8%~9.0%),其中早期(I~Ⅱ期)cKD患者占76.5%。随着年龄增加,CKD患病率逐渐升高且女性患病率明显高于男性(P<0.001)。多因素logistic回归分析显示,CKD与女性、≥60岁、高血压、高尿酸血症、高脂血症等因素独立相关。结论上海市松江区某社区成年人CKD患病率较高,已成为松江区重要的公共卫生问题之一,且女性、≥60岁、高血压、高尿酸血症、高脂血症是CKD的相关因素。需重视CKD的早期防治,避免终末期肾脏病和相关并发症的发生。

Objective To investigate the prevalence and associated factors of chronic kidney diseases (CKD)in adult residents living in a community of Songjiang district,Shanghai.Methods A total of 9257residents aged 20-75years old in Xinqiao township of Songjiang district were selected by random cluster sampling.All the participants were interviewed to complete a set of personal questionnaire and undergo physical examinations.Urine and blood tests including markers of kidney damage and related associated factors with CKD,were carried out.Results Eligible data from 8207 subjects were enrolled in the study.After adjustment for age and gender,the prevalence of CKD was 8.4%(95%CI:7.8%-9.0%),with majority of the patients (76.5%)appeared in the early stage (I and lI )of the disease.The prevalence of CKD increased with age and higher prevalence was seen in females than in males (P<0.001).Results from logistic regression analysis showed that factors as: being elderly or female,having hypertension,hyperuricemia,and hyperlipidemia were all independently associated with CKD.Conclusions The prevalence of CKD appeared relatively high in adult residents of Xinqiao township,Songjiang district where CKD had become a public health problem.Factors as:being female or elderly,hypertension,hypernricemia,and hyperlipidemia were found to be associated with CKD.Our findings suggested that early prevention and control on CKD to reduce the incidence of end-stage renal diseases and related complications had called for more urgent attention.