针灸结合中药保留灌肠治疗溃疡性结肠炎的临床观察

Clinical Research of Combining Acupuncture with Chinese Herbal Retention Enema in the Treatment of Ulcerative colitis

目的:观察针灸结合中药保留灌肠治疗溃疡性结肠炎的疗效。方法:将96例溃疡性结肠炎患者随机分为治疗组和对照组各48例,对照组常规应用美沙拉嗪肠溶片治疗,治疗组在对照组的基础上采用针灸结合中药保留灌肠治疗;治疗4周后观察各自近期临床疗效、电子结肠镜检查情况、Geboes指数评分、IBDQ量表评分和不良反应。结果:治疗组总有效率95. 83%,对照组总有效率81. 25%,两组比较差异有统计学意义(P <0. 05);两组治疗后电子结肠镜检查均显著改善,组间比较,差异均有统计学意义(P <0. 05);治疗组患者治疗后Geboes指数评分和IBDQ量表评分均显著优于对照组(P <0. 05);结论:针灸结合中药保留灌肠治疗溃疡性结肠炎疗效较好。

Objective To observe the efficacy of acupuncture combined with retention enema with traditional Chinese medicine in the treatment of ulcerative colitis.Methods Ninety-six patients with uleerative eolitis were randomly divided into treatment group and control group with 48eases in each group.The control group was treated with basic treatment and oral mesalazine enteric-coated tablets (trade name:Whitney).The treatment group was based on the control group.Acupuncture and traditional Chinese medicine retention enema were used for treatment.After 4weeks of treatment,their clinical effieaey,electronic colonoseopy status,Geboes index score,IBDQ seale score,and adverse reaetions were observed.Results The total effective rate was 95.83%in the treatment group and 81.25%in the control group.The difference between the two groups was statistically significant (P <0.05).After the two groups of treatment,the electronic eolonoseopy was significantly improved.The differences between the two groups were compared.There was statistical significance (P <0.05);After treatment,Geboes index seores and IBDQ scale scores were significantly better in the treat- ment group than in the eontrol group and before treatment (P <0.05).Conclusion Acupuncture combined Retention enema of Chi- nese medicine treatment of ulcerative colitis is more effective than oral mesalazine hydrochloride enteric-coated tablets.