中西医结合治疗儿童哮喘缓解期的疗效观察

Clinical Study on the effect of integrated traditional Chinese and Western medicine on children with asthma during remission

目的:观察中西医结合防治5岁以下儿童支气管哮喘缓解期的临床疗效及对外周嗜酸粒细胞(EOS)的影响。方法:选择淮安市妇幼保健院收治的80例哮喘患儿作为研究对象,随机数字表法分成两组,每组40例。对照组采用辅舒酮吸入;试验组在对照组基础上,采用三伏贴治疗。两组均连续治疗3个月为1个疗程,持续观察1个疗程,随访3月。比较两组哮喘控制与中医证候改善情况,以及外周嗜酸粒细胞水平变化。结果:试验组总有效率92. 5%,较对照组77. 5%高,差异有统计学意义(P <0. 05)。两组患儿治疗后EOS的水平较治疗前均显著降低,且试验组较对照组明显(P <0. 05)。结论:试验组三伏贴联合辅舒酮的治疗方案,可有效控制患儿症状,降低哮喘患儿气道炎性反应,预防哮喘发作。

Objective To observe the effect of integrated traditional Chinese and Western medicine for Preventing and Treating Infant Bronchial Asthma.Methods Eighty children were randomly divided into two groups with 40cases in each group.Matched group inhaled Flixotide Aerosol;The experimental group,which based on the matched group,was treated with Acupoint -application Therapy,respectively,on the first day of the summer first,middle and last volt,in total of 3times,each applied 2-4hours.Both groups were treated continuously for 3months as a course of treatment.Continue to observe 1course ,Followed up for 3months.The improvement of asthma control and TCM syndrome and the change of peripheral eosinophil level were compared between the two groups. Results The total effective rate of the combined group was 92.5%,which was significantly higher than that of the control group in 77.5%(P <0.05).After treatment,the levels of EOS in the two groups were significantly lower than those before treatment,and those levels in the experimental group were significantly lower than those in the matched group (P <0.05).Conclusion Acupoint - application Therapy in Summer has a certain effect in reducing the concentration of serum inflammatory markers,which can effectively improve the airway damage and improve the clinical symptoms.