摘要
目的比较康定贝母、卷叶贝母及暗紫贝母的质量,验证康定贝母作为川贝母来源之一的合理性。方法采用HPLC-ELSD法及TLC法分析康定贝母及川贝母中的卷叶贝母、暗紫贝母,同时对这3种贝母的外观性状、折干率、水分、灰分、醇溶性浸出物和总生物碱的含量进行测定。结果康定贝母的外观性状与卷叶贝母相似,3种贝母的HPLC和TLC图谱均十分相似。其中,卷叶贝母的生物碱含量明显高于康定贝母和暗紫贝母的。结论康定贝母作为川贝母使用具有一定的科学性。
OBJECTIVE To determine whether Fritillaria cirrhosa D. Don var. Ecirrhosa Franch. can be used as F. cirrhosae through the quality comparison of F. cirrhosa D. Don var. Ecirrhosa Franch.,F. cirrhosa D. Don and cultivated F. unibracteata Hsiao et K. C.Hsia. METHODS HPLC and TLC analysis were performed on the three kinds of Fritillaria. The appearance traits,dry discount rate and the content of water,total ashes,alcohol-soluble extract and total alkaloid in samples were analyzed. RESULTS The appearance of bulbus F. cirrhosa var. Ecirrhosa is similar to bulbus F. cirrhosae,and the HPLC and TLC chromatograms of the three samples are very similar. But the content of total alkaloid of the bulbus F. cirrhosae is higher than the other samples. CONCLUSION F. cirrhosa var. Ecirrhosa can be used as F. cirrhosae.
作者
王楠轲
谢慧敏
谢慧淦
徐云
王曙
叶本贵
WANG Nanke;XIE Huimin;XIE Huigan;XU Yun;WANG Shu;YE Bengui(West China School of Pharmacy,Sichuan University,Chengdu,Sichuan,610041P.R.China;Nin Jiom Medicine Manufactory (H.K.)Limited,Hong Kong,P.R.China)
出处
《华西药学杂志》
CAS
CSCD
2018年第6期638-640,共3页
West China Journal of Pharmaceutical Sciences
基金
2017年度中医药现代化研究重点专项(编号:2017YFC1701800)
关键词
康定贝母
卷叶贝母
暗紫贝母
质量
性状
薄层色谱法
高效液相色谱法
总生物碱
Fritillaria cirrhosa D.Don var.Ecirrhosa Franch.
F.cirrhosae
F.unibracteata
Quality
Character
TLC
HPLC
Total alkaloids
