营养强化蛋白复合粉在肝脏外科围手术期的应用

Application of oral compound protein nutrition supplement in hepatic surgery during perioperative period

目的评估营养强化蛋白复合粉在接受计划性肝脏部分切除术患者围手术期应用的安全性和有效性。方法本研究共纳入2017年1-12月间160例因肝细胞癌接受计划性肝脏部分切除术的患者。治疗组82例患者接受营养强化蛋白复合粉的补充疗法。对照组78例患者接受常规低脂高蛋白营养膳食治疗。监测患者血清白蛋白、血清前白蛋白水平,观察患者不良反应。结果经干预后,治疗组的白蛋白水平显著高于对照组(P <0. 05)。围手术期内,治疗组的人血白蛋白使用量和住院天数均显著低于对照组(P <0. 05)。结论口服营养强化蛋白复合粉可显著提高合并低蛋白血症的肝癌患者的白蛋白水平,并减少围手术期人血白蛋白的用量,具有一定的快速康复价值。

Objective To evaluate the safety and efficacy of oral compound protein in perioperative management of patients with hepatocellular carcinoma (HCC).Methods One hundred and sixty patients with HCC scheduled to receive hepatic surgery from January 2017to December 2017were included in the study.Eighty-two patients in the treatment group received oral compound protein, while 78 patients in the control group were given routine low-lipid-high-protein diet.The levels of serum albumin and serum prealbumin were detected and reactions of the patients in the groups were observed closely.Results Following intervention,the levels of serum albumin and serum prealbumin in the treatment group were significantly higher than those in the control group (P <0.05).During the perioperative management period,the total amount of human albumin consumed by the patients and hospitalization time of the treatment group were significantly lower than that of the control group (P <0.05).Conclusion The application of oral compound protein could significantly enhance the albumin level of the hepatic cancer patients complicated with hypoproteinemia,and reduce the consumption of human serum albumin during perioperative period.For this reason,it is beneficial to quick recovery of patients with hepatic surgery to a certain extent.