乳房动脉钙化对冠心病诊断价值研究

The Association between Breast Arterial Calcifications and Risk of Coronary Artery Disease

目的探讨女性乳房动脉钙化与冠心病的关系,并评估乳房动脉钙化对冠心病的诊断价值。方法选择行冠状动脉CT血管造影且行乳腺钼靶扫描的127例女性患者作为研究对象。多因素Logistics回归分析乳房动脉钙化(BAC)分级与冠心病之间的关系,受试者工作曲线评估BAC对冠心病的诊断价值。结果冠心病患者BAC阳性比例高于非冠心病患者;在调整传统的冠心病危险因素后,BAC阳性与冠心病发病独立相关(比值比OR∶2. 51,95%置信区间CI为1. 32～4. 8,P <0. 05)。BAC对冠心病具有诊断价值,BAC明显改善传统危险因素对冠心病的诊断价值。结论 BAC对女性冠心病具有诊断价值。

Objective To explore the relationship between breast arterial calcifications and risk of coronary artery disease and evaluate the diagnosis value of breast arterial calcifications on the elevated risk of coronary artery disease. Methods 127 women who underwent both coronary CTA and digital mammography were selected. A multiple logistic regression analysis was conducted to explore the relationship between breast arterial calcifications and the risk of coronary artery disease. Receiver - operating characteristic (ROC) curves were used to determine the diagnosis value of breast arterial calcifications on the risk of coronary artery disease. Results There was a higher prevalence of breast arterial calcification in coronary artery diseases patients than the non - coronary artery diseases patients. After adjusted the traditional risk factor of coronary artery diseases,BAC was positively associated with CAD in females(OR: 2.51,95% CI: 1.32 ~ 4.8,P<0.05) . BAC had the diagnosis value to predict the risk of CAD in female . Conclusion Breast arterial calcifications on mammography can predict the elevated risk of coronary artery disease.