自拟独活寄生汤治疗腰椎间盘突出症椎间孔镜术后的感觉异常

Clinical observation of the effects of modified Duhuo-Jisheng decoction for treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation

目的评价自拟独活寄生汤治疗腰椎间盘突出症椎间孔镜术后感觉异常的疗效。方法将符合入选标准的89例腰椎间盘突出症椎间孔镜术后感觉异常患者,采用随机数字表法分为对照组44例、治疗组45例。对照组口服甲钴胺胶囊,治疗组口服自拟独活寄生汤。2组均连续治疗4周。采用VAS量表评价下肢疼痛程度,应用尼龙绳实验评价下肢麻木程度;采用Oswestry功能障碍指数(Oswestry Disability Index, ODI)评价腰椎功能;采用WHO生存质量量表(World Health Organization Quality of Life, WHOQOL-BREF)评价生活质量,比较2组患者临床疗效。结果治疗组总有效率为93.3%(42/45)、对照组为75.0%(33/44),2组比较差异有统计学意义(χ^2=5.641,P=0.018)。治疗后,治疗组VAS评分、ODI评分均低于对照组(t值分别为11.440、8.976,P<0.01),尼龙绳实验评分、WHOQOL-BREF评分均高于对照组(t值分别为10.524、6.221,P<0.01)。结论自拟独活寄生汤可明显改善腰椎间盘突出症患者椎间孔镜术后的下肢疼痛、麻木及腰椎功能和生活质量。

ObjectiveTo study the effects of modified Duhuo-Jisheng decoction for treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation. MethodsA total of 89 lumbar disk herniation patients with paresthesia after transforaminal endo-scopic discectomy were divided into the control group (n=44) and the treatment group (n=45) by random number table method. The control group were treated with mecobalamin capsule, and the treatment group treated modified Duhuo-Jisheng decoction. The two groups were treated for 4 weeks. The VAS scale was used to evaluate the pain level of the lower extremities, and the nylon rope test score was used to evaluate the numbness of the lower extremities; and the Oswestry Disability Index was used to evaluate lumbar function; and the World Health Organization Quality of Life (WHOQOL-BREF) was used to evaluate the quality of life. The clinical efficacy of the two groups was compared. ResultsThe total effective rate was 93.3% (42/45) in the treatment group and 75.0% (33/44) in the control group. There were significant differences between the two groups (χ^2=5.641, P<0.05). After treatment, the VAS score and ODI score in the treatment group were significantly lower than those in the control group (t=11.440, 8.976, P<0.01). The nylon rope test score and WHOQOL-BREF score were significantly higher than those of the control group (t=10.524, 6.221, P<0.01). ConclusionsThe modified Duhuo-Jisheng decoction can significantly improve pain and numbness of lower extremities, lumbar function and quality of life in lumbar disk herniationpatients with paresthesia after transforaminal endo-scopic discectomy.