芳香酚-甲醇选择性邻位甲基化反应研究进展

Research progress on selective ortho-methylation between aryl phenols and methanol

围绕甲基化反应催化剂、邻位甲基化反应机理以及甲醇副反应,评述了甲基化反应催化剂、金属氧化物邻位甲基化活性中心以及甲醇副反应对氧化物催化剂结构和性能影响,并指出易于掺杂金属离子调变表面酸碱性的尖晶石结构金属氧化物,或可作为高选择性初级或二级甲基化反应催化剂的研究重点。

Focusing on methylation catalysts,ortho-methylation mechanism and side reaction of methanol,this paper reviews the catalysts for methylation reaction,the active centers of metal oxide catalysts for ortho-methylation and the influences of side reaction concerning methanol on the structure and performance of catalysts. It also points out that the metal oxides with spinel structure,whose surface acidity and basicity can be finely tuned by metal ion doping,will be the research key for highly selective primary or secondary methylation catalysts.