健脾疏肝汤治疗功能性消化不良肝胃不和证临床观察

Clinical Observation of Jianpi Shugan Tang for Functional Dyspepsia with Syndrome of Disharmony between Liver and Stomach

目的:观察健脾疏肝汤治疗功能性消化不良肝胃不和证的临床效果。方法:将70例功能性消化不良肝胃不和证患者进行分组研究,根据门诊单双日顺序将患者分为观察组和对照组,每组35例。对照组使用多潘立酮片治疗,观察组以自拟健脾疏肝汤治疗,疗程为4周,随访6月。比较2组的临床疗效,治疗前后评定2组患者的症状评分。结果:观察组总有效率94.29%,对照组总有效率71.43%,2组比较,差异有统计学意义(P <0.05)。2组上腹灼热感、上腹痛、早饱、腹胀评分均较治疗前下降,差异均有统计学意义(P <0.01);观察组4项症状评分均低于对照组,差异均有统计学意义(P <0.01)。结论:疏肝健脾和胃法方药无论是在短期缓解症状还是远期疗效方面均较西药治疗有更为显著的效果,值得在临床实践中应用。

Objective:To observe the clinical effect of Jianpi Shugan tang for functional dyspepsia with syndrome of disharmony between liver and stomach. Methods:Divided 70 cases of patients with functional dyspepsia with syndrome of disharmony between liver and stomach into the observation group and the control groupaccording to the random number tablein clinic, 35 cases in each group. The control group received Domperidone tablets, while the observation group received self-made Jianpi Shugan tang. The treatment lasted for 4 weeks,and follow-ups for 6 months. Compared the clinical effect in both groups,and evaluated the symptom scores of patients in both groups before and after treatment. Results:The total effective rate was 94.29% in the observation group and 71.43% in the control group,difference being significant(P<0.05). Scores of burning sensation in the upper abdomen,pain in the upper abdomen, early satiety and abdominal distension of both groups were lower than those before treatment, differences being significant(P<0.01);each score in the observation group was lower than that in the control group,differences being significant(P < 0.01). Conclusion:The prescription based on the method of dispersing liver,invigorating spleen and harmonizing stomach has more significant effect in both the short-term inhibitory symptoms and the long-term clinical effect when compared with western medicine, which is worthy of clinical application.