经皮冠状动脉介入术治疗老年急性心肌梗死效果

The effect of percutaneous coronary intervention on elderly patients with acute myocardial infarction

目的比较分析经皮冠状动脉介入术与溶栓治疗老年急性心肌梗死的临床效果。方法将寿光市人民医院2017年6月-2018年3月收治的186例老年急性心肌梗死患者随机分为观察组和对照组各93例。对照组采用溶栓治疗,即口服氯吡格雷以及静脉滴注尿激酶,观察组使用经皮冠状动脉介入术治疗。比较两组前后的心功能以及血清TnI、CK-MB、SOD和ET-1水平。结果观察组患者的有效率明显高于对照组;治疗后,观察组患者左心室射血分数、左心室舒张末期内径、左心室后壁厚度、TnI、CK-MB、ET-1、SOD水平优于对照组,差异均有统计学意义(P<0.05)。结论经皮冠状动脉介入术对老年急性心肌梗死的治疗效果明显优于溶栓治疗,值得临床推广。

Objective To compare the clinical effects of percutaneous coronary intervention and thrombolytic therapy on elderly patients with acute myocardial infarction. Methods 186 elderly patients with acute myocardial infarction in Shouguang People’s Hospital during June 2017-March 2018 were randomly divided into observation group and control group,93 cases in each group. The control group was treated with thrombolytic therapy,oral clopidogrel and intravenous urokinase,the observation group was treated with percutaneous coronary intervention. The cardiac function and serum levels of TnI,CK-MB,SOD and ET-1 were compared between the two groups. Results The effective rate of the patients in the observation group was significantly higher than that of the control group. After treatment,the level of left ventricular ejection fraction,left ventricular end diastolic diameter,left ventricular posterior wall thickness,TnI,CK-MB,ET-1 and SOD level in the observation group were better than those in the control group. The differences were statistically significant(P<0.05). Conclusion Percutaneous coronary intervention is superior to thrombolytic therapy on elderly patients with acute myocardial infarction,it is worth of clinical promotion.