降钙素原在临床感染中的应用

The Application of Procalcitonin in Clinical Infection

本文检索Pub Med、EMBase、Cochrane图书馆、中国期刊全文数据库、维普中文数据库等资料,探索降钙素原在感染及预防感染中的作用,为合理使用抗菌药物提供依据。文献显示降钙素原对于感染的专属性和敏感性都较高,持续监测降钙素原的变化情况,并根据其变化水平来决定是否使用抗菌药物,能够量化已经存在感染或存在感染风险的患者的感染程度。

To explore the role of procalcitonin in infection and prevention of infection and to provide evidence for rational use of antibacterial drugs,in this article,the computer was used to retrieve the articles used in the infection of Pub Med,EMBase,Cochrane Library,Chinese journal full-text database and Weipu Chinese database. The results demonstrated that procalcitonin original has high specificity and sensitivity to infection. The decision whether use antibacterial drugs or not depends on the continuous monitoring of the procalcitonin original and the changes of calcitonin level. The extent of infection in patients who are already infected or at risk can be quantified in this way.