中西医结合治疗痛性糖尿病周围神经病变32例

Clinical effect of integrated traditional Chinese and Western medicine therapy in treatment of painful diabetic peripheral neuropathy: An analysis of 32 cases

目的:观察中西医结合治疗气虚血瘀型痛性糖尿病周围神经病变的临床疗效。方法:将64例气虚血瘀型痛性糖尿病周围神经病变患者随机分为对照组、治疗组各32例,对照组采用普瑞巴林、甲钴胺治疗,治疗组在对照组治疗的基础上加用身痛逐瘀汤治疗。比较2组综合疗效、疼痛视觉模拟(VAS)评分、神经功能情况。结果:总有效率治疗组为84. 4%,对照组为71. 9%,组间比较,差异有统计学意义(P <0. 05); 2组VAS评分、神经功能治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P <0. 05)。结论:中西医结合治疗气虚血瘀型痛性糖尿病周围神经病变有较好的临床疗效。

Objective :To investigate the clinical effect of integrated traditional Chinese and Western medicine therapy in the treatment of painful diabetic peripheral neuropathy with Qi deficiency and blood stasis.Methods :A total of 64 patients with painful diabetic peripheral neuropathy with Qi deficiency and blood stasis were randomly divided into control group and treatment group,with 32 patients in each group.The patients in the control group were given pregabalin and mecobalamin,and those in the treatment group were given Shentong Zhuyu decoction in addition to the treatment in the control group.The two groups were compared in terms of overall response,Visual Analogue Scale (VAS)score,and neurological function.Results:There was a significant difference in overall response rate between the treatment group and the control group(84.4%vs 71.9%,P <0.05).Both groups had significant changes in VAS score and neurological function after treatment,and there were significant differences between the two groups after treatment(P <0.05).Conclusion:Integrated traditional Chinese and Western medicine therapy has a good clinical effect in the treatment of painful diabetic peripheral neuropathy with Qi deficiency and blood stasis.