某医院多重耐药菌感染分布趋势与耐药性分析

Distribution trend and antibiotics resistance analysis of Multi-drug resistance organism in a hospital

目的研究医院多重耐药菌感染分布趋势及耐药性变化情况。方法通过回顾性分析,对某医院住院患者多重耐药菌感染分布及耐药情况进行统计分析。结果该医院连续3年共检出病原菌4889株,其中含多重耐药菌,占18.82%,且逐年升高的趋势。多重耐药菌感染部位分布以下呼吸道感染、泌尿系统感染和血液系统感染分居前3位。多重耐药菌以耐碳青霉烯类鲍曼不动杆菌占首位,其次是MRSA。CRAB仅对左氧氟沙星相对敏感,MRSA对替加环素和万古霉素完全耐药,PDR—PA对头孢吡肟比较敏感。结论该医院临床分离病原菌普遍耐药,多重耐药菌的检出率呈上升趋势,应将感染防控重点放到控制多重耐药菌在院内蔓延方面。

Objective To investigate distribution trend and changing of antibiotics resistance of Multi -drug resistance organism (MDRO)in hospital.Method Retrospective study was used to statistical analysis distribution and antibiotics resistance of MDRO of inpatient in a hospital.Result 4889 strains of pathogenic bacteria in this hospital had been found in past three years,including 18.82% MDRO which showed an increasing trend year by year.As for MDRO infection site, lower respiratory tract,urinary system and blood system were three highest infection rates.Carbapenems resistant acinetobactor baumannii and MRSA were two most common MDRO.CRAB was only relative sensitive to levofloxacin,MRSA was total resistant to Tigecycline and vancomycin,PDR -PA was more sensitive to cefepime.Conclusion Clinical isolated pathogenic bacteria in this hospital is widespread resistance,MDRO detect rate has increasing trend,MDRO spread control in hospital should be the priority of infection prevention and control.