不同剂量米索前列醇在初孕妇孕早期无痛人流术中的应用效果

Application effect of different doses of misoprostol on early pregnant women with painless abortion

目的探讨不同剂量米索前列醇在初孕妇孕早期无痛人流术中的应用效果。方法选取2015年3月—2017年1月在盐城市亭湖区黄尖中心卫生院妇产科行无痛人流术的孕早期初孕妇70例,采用随机数字表法分为A、B组,各35例。术前均给予米索前列醇,A组给药剂量为400μg,B组为600μg。比较两组初孕妇术中出血量及无阻力扩宫率、术后镇痛率。结果 A组术中出血量少于B组,无阻力扩宫率高于B组(P<0.05);两组患者术后镇痛率比较,差异无统计学意义(P>0.05)。结论 400μg米索前列醇可降低初孕妇孕早期无痛人流术中出血量,提高宫颈软化效果,有效减轻疼痛程度。

Objective To investigate the application effect of different doses of misoprostol on early pregnant women with painless abortion.Methods A total of 70 cases of early pregnant women with painless abortion were admitted from March 2015to January 2017in Yancheng Tinghu District Huangjian Center Hospital,which were divided into A,B group according to random number table,35 cases in each group.All patients were given misoprostol,A group was 400μg,B group was 600μg.The intraoperative bleeding volume,the rate of resistanceless to dilatation and postoperative analgesia were compared between the two groups.Results The A group of intraoperative bleeding volume was less than B group,and the rate of resistanceless to dilatation was higher than B group (P<0.05);there was no significant difference in the rate of postoperative analgesia between the two groups (P>0.05).Conclusion 400μg misoprostol can reduce the intraoperative bleeding volume and improve the cervical softening effect of early pregnant women with painless abortion,and can effectively relieve postoperative pain.