针灸-免疫:现状与未来

Acupuncture and Moxibustion and Immunity:the Actuality and Future

调控免疫过程是针灸发挥作用的关键环节,分析针灸作用后的免疫机制,能较好地解释针灸发挥治疗效应的细胞、分子机制。本文重点从针灸对免疫相关性疾病的治疗,对免疫细胞、分子、信号通路的调控等环节,初步诠释针灸对免疫系统的影响及与针灸治疗疾病的相关性。

Immunity reaction has been regarded as a key step for clinical acupuncture and moxibustion treatment.In the present paper,we review current situations about studies on acupuncture-moxibustion induced immunoregulation from 1)related project fundings of National Natural Science Foundation(NCFS)of China from 1989—2017;2)papers published in SCI and Chinese medical journals from 2010—2018;3)clinical conditions or disorders treated by acupuncture and moxibustion and their clinical therapeutic effects;4)the commonly used acupoints for studying immune regulation functions;5)some mechanisms of innate immunity and adaptive immunity involved;and 6)immune adjustment pathways involved.Moreover,in our future studies,we suggest to pay more attention to 1)the detailed cellular molecular mechanisms;2)interactions among the immune cells,the immune cells and non-immune cells and cytokines responsible for regulation effects of acupuncture-moxibustion;3)interrelationship of different systems as skin-brain axis,brain-intestinal axis,nerve-blood vessel unit of brain tissues,etc.involving acupuncture-moxibustion induced immunoregulation by using new techniques as proteomics,genomics,two-photon imaging technology,tracer technique,cryo-electronic microscope technology,etc.