各年龄段正常玻璃体水分子运动速度的初步探讨

Movement speed of water molecules in normal vitreous body at different ages: a preliminary study

目的:初步了解不同年龄段正常玻璃体水分子运动速度的规律,以便早期发现玻璃体异常,及早治疗或干预。方法:回顾性分析2016年7月—2017年12月共162名(324只眼球)眼部发育正常人的MRI资料,按年龄大小分成9组,即A组0～<10岁、B组10～<20岁、C组20～<30岁、D组30～<40岁、E组40～<50岁、F组50～<60岁、G组60～<70岁、H组70～<80岁、Ⅰ组80～<90岁,分别对各年龄组两只眼球玻璃体进行MR弥散加权成像(Propeller-DWI),同时测量感兴趣区的表观扩散系数(ADC)值,计数并进行统计学分析。结果:经方差分析显示眼球玻璃体ADC值随年龄的增长呈先上升后下降随后趋于稳定的趋势,组间比较P=0.00,差异有统计学意义。结论:眼球玻璃体水分子运动速度随年龄的增长呈先上升后下降随后趋于稳定的趋势。

Objective:To understand the rule of velocity of water molecules in normal vitreous body at different ages,so as to find vitreous body abnormalities early,and to take early treatment or intervention.Methods:From July 2016 to December 2017,a total of 162 normal persons (324eyes)were retrospectively analyzed.MRI data was divided into 9 groups according to age:A group 0-<10years old,B group 10-<20years old,C group 20-<30years old,D group 30-<40years old,E group 40-<50years old,F group 50-<60years old,G group 60-<70years old,H group 70-<80years old,I group 80-<90 years old.MR diffusion weighted imaging (Propeller-DWI)of two eyeballs and vitreous body in each age group was performed, and the apparent diffusion coefficient (ADC)value of the region of interest was measured.Results:Variance analysis showed that the ADC value of the vitreous body increased first and then decreased with age,and then tended to be stable.There was a statistically significant difference between the two groups (P=0.00).Conclusion:The movement speed of normal vitreous body water molecules rises first and then decreases with the increase of age,and then tends to be stable.