甲状腺结节中甲状腺癌的筛查方法与评价

Evaluation of screening methods of thyroid carcinoma in thyroid nodules

甲状腺结节是一种常见的甲状腺疾病,发病率高。在女性人群中甲状腺结节发生率为22%~58%,在甲状腺结节中甲状腺恶性肿瘤占5%-15%,因而要注重对甲状腺结节的肿瘤筛查。临床检查除核素、超声检查、细针穿刺抽吸活检等常用检查方法外,应该同时联合甲状腺肿瘤标志物检测以提高甲状腺癌的检出率。研究证实甲状腺肿瘤标志物在甲状腺肿瘤的诊断及疗效监测具有重要临床意义。在甲状腺癌术前、术后合理应用甲状腺癌血清标志物检测有助于对手术术式的选择及术后肿瘤残留率和复发的评估。

Thyroid nodule is a common thyroid disease with high incidence,as high as 22%-58% in the female population,and thyroid malignancies accounted for 5%-15% in this disease,so we should pay attention to the tumor screening of thyroid nodules.In addition to routine examination methods such as nuclide,ultrasonography and needle aspiration biopsy,the detection of thyroid tumor markers should be combined to improve the detection rate of thyroid cancer.Studies have confirmed that thyroid tumor markers have important clinical significance in the diagnosis and therapeutic monitoring of thyroid tumors.The reasonable application of screening thyroid cancer markers before and after surgery for thyroid cancer is helpful to select the surgical procedure and evaluate the residual rate and recurrence of postoperative tumor.