肝动脉栓塞治疗肝血管瘤的临床治疗效果分析和理性思考

Clinical analysis and rational consideration of hepatic artery embolization for treatment of hepatic hemangioma

目的探讨肝动脉栓塞治疗肝血管瘤的临床治疗效果和理性思考。方法 69例肝血管瘤患者,按照随机数字表法分为外科手术治疗组(34例)和肝动脉栓塞治疗组(35例)。外科手术治疗组患者采取外科手术治疗,肝动脉栓塞治疗组患者采取肝动脉栓塞治疗。比较两组疗效,肝血管瘤缩小>1/2体积时间、住院时间,治疗前后患者生存质量(QOL)评分、幸福指数,并发症发生情况。结果肝动脉栓塞治疗组患者总有效率为100.00%,高于外科手术治疗组的76.47%,差异具有统计学意义(P<0.05)。治疗前,两组患者生存质量评分、幸福指数比较差异无统计学意义(P>0.05);治疗后,两组患者生存质量评分、幸福指数均较本组治疗前改善,且肝动脉栓塞治疗组改善幅度大于外科手术治疗组,差异具有统计学意义(P<0.05)。肝动脉栓塞治疗组患者肝血管瘤缩小>1/2体积时间、住院时间均短于外科手术治疗组,差异具有统计学意义(P<0.05)。肝动脉栓塞治疗组并发症发生率为5.71%,显著低于外科手术治疗组的35.29%,差异具有统计学意义(P<0.05)。结论肝动脉栓塞治疗肝血管瘤的效果理想。

Objective To discuss the clinical effect and rational consideration of hepatic artery embolization for treatment of hepatic hemangioma. Methods A total of 69 hepatic hemangioma patients were divided by random number table method into surgical group (34 cases) and hepatic artery embolization group (35 cases). Surgical group received surgical therapy, and hepatic artery embolization group received hepatic artery embolization therapy. Comparison were made on efficacy, hepatic hemangioma shrinks > 1/2 volume time, hospitalization time, quality of life (QOL) score, happiness index before and after treatment, and occurrence of complications between the two groups. Results Hepatic artery embolization group had higher total effective rate as 100.00% than 76.47% in surgical group, and the difference was statistically significant (P<0.05). Before treatment, both groups had no statistically significant differences in quality of life score and happiness index (P>0.05). After treatment, both groups had improved quality of life score and happiness index than those before treatment, and hepatic artery embolization group had larger improvement range than surgical group. The differences were statistically significant (P<0.05). Hepatic artery embolization group had shorter hepatic hemangioma shrinks >1/2 volume time and hospitalization time than surgical group, and the differences were statistically significant (P<0.05). Hepatic artery embolization group had significantly lower incidence of complications as 5.71% than 35.29% in surgical group, and the difference was statistically significant (P<0.05). Conclusion Hepatic artery embolization shows ideal effect in the treatment of hepatic hemangioma.