摘要
载脂蛋白A5(apolipoprotein A5,Apo A5)是载脂蛋白家族成员之一。它是三酰甘油代谢的重要调控因子,调控血浆中三酰甘油含量。Apo A5的基因多态性影响人体三酰甘油代谢,与动脉粥样硬化性心血管疾病密切相关,其中对–1131T>C,c.56C>G,c.553G>T研究最多。
Apolipoprotein A5 (Apo A5) is a novel member in apolipoprotein family, which is proven to be an important regulator in triglyceride metabolism, especially in adjusting the TG content in plasma. Apo A5 gene polymorphisms affect triglyceride metabolism and atherosclerotic cardiovascular diseases. The research focuses on–1131T>C, c.56C>G, and c.553G>T.
作者
刘雅琼
赵旺
赵水平
LIU Yaqiong;ZHAO Wang;ZHAO Shuiping(Department of Cardiovascular Medicine,Second Xiangya Hospital,Central South University,Changsha 410011,China)
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2018年第12期1358-1363,共6页
Journal of Central South University ：Medical Science
基金
国家自然科学基金(81500234)~~
关键词
载脂蛋白A5
基因多态性
三酰甘油
动脉粥样硬化性心血管疾病
冠心病
apolipoprotein A5
gene polymorphism
triglyceride
atherosclerotic cardiovascular diseases
coronary artery heart disease
