颌骨非霍奇金淋巴瘤3例并文献复习

Non-Hodgkin's lymphoma in the jaw: A report of 3 cases and literature review

回顾性分析3例颌骨非霍奇金淋巴瘤患者的临床资料,并复习相关文献。探讨发生于颌骨的非霍奇金淋巴瘤的临床表现、影像学特点及诊断方法。3例均发生于上颌骨,早期为无痛性包块,CT表现为溶骨性病变。2例行活体标本检查示弥漫大B细胞淋巴瘤,1例行上颌骨扩大切除术后病理检查结果示浆母细胞瘤。颌骨非霍奇金淋巴瘤临床及影像学表现无特异性,早期行病变区组织活体标本检查术并病理检查可辅助诊断。

To investigate the clinical manifestations, imaging features, and diagnosis for non-Hodgkin’s lymphoma in the jaw, we retrospectively analyzed 3 cases of non-Hodgkin’s lymphoma in the jaw and reviewed relevant literature. Th ree patients’ lesion occurred in the maxilla with early painless masses. Two patients were diagnosed as diff use large B-cell lymphoma via biopsy, and one patient underwent maxillofacial resection with pathological examination which showed plasmaoblastoma lymphoma. Non-Hodgkin’s lymphoma in the maxilla is rare and easily misdiagnosed due to the atypical clinical features. Biopsy at the early stage of the lesion and pathological examination can assist the diagnosis for non-Hodgkin’s lymphoma.