摘要
目的了解上海市孕产妇乙型肝炎(乙肝)表面抗原(HBsAg)阳性率及新生儿乙肝疫苗(HepB)与乙肝免疫球蛋白(HBIG)接种率。方法收集2015-2017年上海市所有71家产科机构孕产妇的HBsAg检测结果和新生儿首剂HepB(HepB1)、HBIG接种情况,进行描述性分析。结果 2015-2017年共登记孕产妇611 151人,HBsAg检测率为99.03%, HBsAg阳性率为4.27%,其中本市、外来孕产妇HBsAg检测率分别为99.49%、98.53%,HBsAg阳性率分别为3.16%、5.50%。HBsAg阳性母亲所生新生儿HepB1+HBIG联合接种率为91.14%(24 280/26 639),其中本市、外来孕产妇所生新生儿分别为92.55%、90.23%。结论上海市孕产妇HBsAg阳性率低,应加强孕产妇及其新生儿(特别是外来人群)的母婴传播阻断措施。
Objective To determine the positivity rate of maternal hepatitis B surface antigen(HBsAg), and the coverage of neonatal hepatitis B vaccine(HepB) and use of hepatitis B immunoglobulin(HBIG). Methods We collected maternal HBsAg test results from all 71 obstetric institutions and neonatal HepB1 and HBIG usage data in Shanghai during 2015-2017 for a descriptive analysis. Results A total of 611 151 pregnant women were included in the study, with an HBsAg detection rate of 99.03% and an HBsAg positivity rate of 4.27%. The detection rate was 99.49% among local mothers and 98.53% among non-local mothers, with HBsAg positivity rates of 3.16% and 5.50%, respectively. Coverage of HepB1+HBIG use was 91.14%(24 280/26 639) among infants born to HBsAg-positive mothers, with rates of 92.55% and 90.23% for local and non-local newborns. Conclusions The maternal HBsAg positivity rate was low in Shanghai. Interruption of mother-to-child transmission should be strengthened, especially for the non-local population.
作者
陆瑾
孙晓冬
刘捷宸
许振慧
黄卓英
Lu Jin;Sun Xiaodong;Liu Jiechen;Xu Zhenhui;Huang Zhuoying(Huangpu District Center for Disease Control and Prevention,Shanghai 200023,China;Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200051, China)
出处
《中国疫苗和免疫》
北大核心
2018年第6期654-657,共4页
Chinese Journal of Vaccines and Immunization