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断食疗法的研究现状及前景展望 被引量:1

Fasting: Recent development and prospects
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摘要 断食疗法作为一种饮食干预方式,以限制热量摄入为核心,通过改变断食的强度及频率衍生出不同形式。断食不仅是减重的有效手段,在调节代谢等方面也具有积极意义,其作用机制主要涉及脂解作用、增强产热效应、调节自噬、促进胰岛β细胞增殖、抑制炎症反应等。本文主要综述了断食疗法的种类、减轻体重和改善代谢等方面的作用及机制。 Fasting is a dietary intervention based on restricted energy intake, which has different forms of frequency and intensity, and is effective at reducing body weight and improving metabolic health. The cellular and molecular mechanisms of fasting involve lipolysis, increase of thermogenesis, regulation of autophagy, modulation of β cell regeneration and suppression of inflammation. This review focuses on the updates of patterns, benefits, and mechanisms of fasting.
作者 陈力嘉 洪洁 宁光 Chen Lijia;Hong Jie;Ning Guang(Shanghai Clinical Center for Endocrine Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China)
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2018年第12期1072-1076,共5页 Chinese Journal of Endocrinology and Metabolism
基金 国家自然科学基金项目 (81471060、81870582) 国家973项目 (2015CB553601).
关键词 断食疗法 肥胖 代谢性疾病 Fasting Obesity Metabolic disease
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