临床患者自身抗体阳性情况调查及输血对策分析

Investigation on autoantibody positive situation in clinical patients and countermeasure analysis of blood transfusion

目的回顾分析临床不同疾病患者存在自身抗体情况,总结不同自身抗体情况下不同的输血对策。方法 2016年3月-2018年3月存在自身抗体的16例患者,分析不同疾病自身抗体阳性情况,并根据不同情况制定输血对策。结果 16例患者中女性占比较高,占68. 8%(11/16),不同疾病自身抗体阳性情况以自身免疫性疾病略高,占37. 50%(6/16),抗体类型以冷抗体为主,占50. 00%(8/16)。结论临床存在着不同类型的自身抗体情况,冷抗体型输血注意保温,缓慢输注,可以保证疗效;温抗体型患者应以最小量输血,可以配合使用糖皮质激素,与临床医生密切联系。

Objective To review and analyze the status of autoantibodies in patients with different clinical diseases and summarize the different blood transfusion strategies in the case of different autoantibodies. Methods From March 2016 to March 2018,16 patients with autoantibodies were analyzed. The positive rate of autoantibodies in different diseases was analyzed,and blood transfusion strategies were formulated according to different situations. Results Among the 16 patients,the rate of women was a little higher,accounting for 68. 8%( 11/16). The positive rate of autoantibodies in different diseases was slightly higher than that in autoimmune diseases,accounting for 37. 50%( 6/16). The cold autoantibodies were the main type,accounting for50. 00%( 8/16). Conclusion There are different types of autoantibodies in the clinic. Patients with cold autoantibodies need to pay attention to heat preservation and slow infusion to ensure the curative effect. Patients with warm autoantibodies should be given the minimum amount of blood along with the use of glucocorticoids,and keep in close contact with clinicians.