超声乳化白内障摘除术治疗轻度白内障的效果及对患者泪液炎症因子的影响

Clinical effect of phacomulsification on mild cataract and its effect on inflammatory cytokines in tears

目的分析超声乳化白内障摘除术治疗轻度白内障患者的效果及对泪液炎症因子的影响。方法将2016年1月至2017年1月收治的104例轻度白内障患者随机分为甲、乙两组,每组52例。甲组施予小切口非超声乳化囊外摘除术,乙组施予超声乳化白内障摘除术,回顾性分析其泪膜破裂时间(BUT)、泪液分泌情况(SIT)、角膜内皮细胞密度(CED)及角膜变异系数(CV)、白细胞介素-6(IL-6)、肿瘤坏死因子α(TNF-α)、白细胞介素-8(IL-8)。结果术后乙组BUT、SIT水平均高于甲组,CED、L-6、IL-8以及TNF-α水平均低于甲组,差异有统计学意义(P<0.05),乙组CV水平[(41.25±4.30)%]与甲组[(41.20±4.33)%]比较,差异未见统计学意义(P>0.05)。结论轻度白内障患者施予超声乳化白内障摘除术治疗临床效果显著,可改善泪液炎症因子,临床价值高。

ObjectiveTo analyze the effect of phacomulsification on mild cataract and its effect on inflammatory cytokines in tears.MethodsA total of 104 patients with mild cataract admitted in Heji Hospital Affiliated to Changzhi Medical College from January 2016 to January 2017 were randomly divided into group A and group B, with 52 cases in each group. The patients in group A were treated with small incision phacoemulsification extracapsular cataract extraction, and the patients in group B were treated with phacomulsification. The tear break-up time(BUT), schirmer Ⅰ test(SIT), corneal endothelial cell density(CED), coefficient of variation(CV), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α) and interleukin-8(IL-8) of the two groups were observed.ResultsAfter the operation, the levels of BUT and SIT in group B were higher than those in group A, the levels of CED, IL-6, IL-8 and TNF -α were lower than those in group A, there were significant differences (P<0.05). The level of CV in group A was(41.25±4.30)%, which was(41.20±4.33)% in group B, there was no significant difference (P>0.05).ConclusionsThe effect of phacomulsification on mild cataract is significant, which can improve the inflammatory cytokines in tears, and has high application value.