摘要
紫檀芪(3,5-二甲氧基-4’-羟基二苯乙烯)是一种主要存在于蓝莓、葡萄和花榈木中的多酚类化合物。已有的研究发现紫檀芪具有抗肺癌、乳腺癌、胃癌、结肠癌等多种肿瘤的抗癌作用。其作用机制涉及调控影响多种肿瘤生物学特性。此外,紫檀芪具有比白藜芦醇更高的生物利用度和生物活性,其抗肿瘤作用和机制值得深入探讨和研究。
Pterostilbene(3,5-dimethoxy-4’-hydroxystilbene) is a polyphenolic compound primarily found in blueberries, grapes, and a tree wood, pterocarpus marsupium. Studies demonstrate that pterostilbene inhibits a variety of cancers, such as lung, breast, stomach, colon, etc. The anti-cancer activities are related to the regulation of several hallmarks of cancer. Moreover, pterostilbene exhibits much greater bioavailability and bioactivity than resveratrol which warrants further investigation in the anti-cancer functions and mechanisms.
作者
张晓雁
张娇
徐丽群
马志强
狄守印
高原
李小飞
闫小龙
张红梅
Xiaoyan ZHANG;Jiao ZHANG;Liqun XU;Zhiqiang MA;Shouyin DI;Yuan GAO;Xiaofei LI;Xiaolong YAN;Hongmei ZHANG(Department of Clinical Oncology,Xijing Hospital, the Fourth Military Medical University,Xi'an 710032,China;Department of Thoracic Surgery,Tangdu Hospital, the Fourth Mihtary Medical University,Xi'an 710038,China;Battalion 5,the First Brigade of Cadets,the Fourth Military Medical University,Xi'an 710032, China)
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2018年第12期931-936,共6页
Chinese Journal of Lung Cancer
基金
国家自然科学基金(No.81572699
No.81871866)资助~~
关键词
紫檀芪
肿瘤
凋亡
增殖
侵袭
Peterostilbene
Neoplasms
Apoptosis
Proliferation
Invasion