摘要
Before you start your own clinical trial,you should empower yourselves the literature appraisal tool.Below is the first chapter of a whole series of evidencebased teaching manual.After reading the manual,you will be able to appraise other authors"articles with confidence.Chapter one deals with simple statistics for clinicians.Normal distribution and probability of "1 in 20"are fundamental to statistical testing.Central limit theorem suggests sample size of at least 30.Forest plot,point estimate and confidence intervals are explained,together with the difference between staffs- tical significance and clinical significance.Student t test is used in parametric testing while chi square test is used in Non-parametric test.