柴胡二白汤治疗顽固性便秘临床观察

Clinical Observation on Chaihu Erbai Decoction in the Treatment of Intractable Constipation

目的探讨柴胡二白汤治疗顽固性便秘临床疗效。方法将2015年10月—2017年10月在本院进行顽固性便秘治疗的36例患者作为本次药物治疗的研究对象,并将其分为对照组与观察组各18例。分别给予不同方式实施治疗:常规治疗(比沙可定肠溶片)与柴胡二白汤(柴胡、黄芩、白芍、白术、升麻、枳壳、元参、火麻仁、五指毛桃)治疗。比较2组患者治疗后的临床疗效及排便相关指标情况。结果观察组(88.89%)与对照组(72.22%)临床疗效比较无明显差异,P>0.05;观察组与对照组各项排便指标改善情况比较差异无统计学意义,P>0.05。结论比沙可定肠溶片与柴胡二白汤在治疗顽固性便秘中其通便疗效相似,但柴胡二白汤改善效果优于比沙可定肠溶片,故更值得进一步推广使用。

Objective To explore the clinical effect of Chaihu Erbai decoction in the treatment of intractable constipation. Method From October 2015 to October 2017,36 patients with intractable constipation were treated in our hospital. They were divided into control group and observation group. They were treated with routine treatment( Bishakedine enteric-coated tablet) and Chaihu Erbai decoction( Radix Bupleurum,Scutellaria baicalensis,Radix Paeoniae Alba,Atractylodes macrocephala,Radix Constanta,Fructus Aurantii Fructus Aurantii,Radix Aurantii,Fructus Magnolia and Peach with five fingers) respectively. The clinical effect and defecation related indexes were compared between the two groups. Results The clinical effect was compard between the observation group( 88. 89%) and the control group( 72. 22%). There was no significant difference( P > 0. 05). There was no significant difference between the observation group and the control group in the improvement of defecation indexes( P > 0. 05). Conclusion The curative effect of Bishakedine enteric-coated tablets and Chaihu Erbai decoction in the treatment of refractory constipation is similar( P > 0. 05). But the improvement effect of Chaihu Erbai decoction is better than that of Bishakedine enteric-coated tablets,so it is worth further popularizing and using.