加减温胆汤治疗小儿肠系膜淋巴结炎(痰热互结型)临床观察

Clinical Observation on Modified Wendan Decoction in Treating Mesenteric Lymphadenitis in Children

目的探讨加减温胆汤治疗小儿肠系膜淋巴结炎(痰热互结型)的疗效及安全性。方法任意选取2014年1月—2017年12月诊断为痰热互结型小儿肠系膜淋巴结炎患儿76例,按照1∶1的分配比例分成2组,各38例,其中对照组给予西药治疗,治疗组在此基础上加用自拟加减温胆汤,对治疗前后临床疗效进行比较,并随访复发率。结果治疗组治疗后淋巴结横、纵径均明显低于对照组(P <0. 05)。治疗组平均腹痛缓解时间、退热时间少于对照组(P <0. 05)。治疗组总有效率为89. 47%,高于对照组的65. 79%(P <0. 05)。2组患儿腹痛复发率比较差异无统计学意义(P> 0. 05)。结论相较于单纯西药治疗,辅助加减温胆汤对于治疗痰热互结型小儿肠系膜淋巴结炎具有显著优势,能明显缩小肿大淋巴结,改善症状,具有推广价值。

Objective To explore the effect and safety of modified Wendan decoction in treating mesenteric lymphadenitis in children.Methods From January 2014 to December 2017,76 children with mesenteric lymphadenitis diagnosed as phlegm-heating type in children were divided into two groups according to the ratio of 1: 1,with 38 cases in each group. The control group was treated with western medicine.On the basis of this,the treatment group added the self-made Wendan decoction. The clinical efficacy was compared. The recurrence rate was followed-up. Results The transverse and longitudinal diameters of lymph nodes in the treatment group were significantly lower than those in the control group( P < 0. 05). The average abdominal pain relief time and fever time in the treatment group were less than those in the control group( P < 0. 05). The total effective rate of the treatment group was 89. 47%,which was higher than that of the control group( 65. 79%)( P < 0. 05). There was no significant difference in the recurrence rate of abdominal pain between the two groups( P > 0. 05).Conclusion Compared with simple Western medicine treatment,the modified Wendan decoction has significant advantages in the treatment of mesenteric mesenteric lymphadenitis in children,which can significantly reduce the enlarged lymph nodes and improve symptoms,and has a promotion value.