肺磨玻璃影CT特征与腺癌组织病理学相关性研究进展

Research progress on correlation between CT features of pulmonary ground glass opacity and histopathology of lung adenocarcinoma

随着多层螺旋计算机断层扫描(CT)的广泛使用和诊疗水平的提高,肺部磨玻璃影(ground glass opacity,GGO)病变的发病率正在增加。GGO病因复杂,病理类型多样,除了良性病变,GGO可以是特定类型的肺腺癌或其侵入性病变。部分学者认为其与早期肺腺癌关系紧密。在临床工作中,肺癌病理组织学对于肺癌的预后判断和治疗非常关键,但在一般情况下要通过手术、支气管镜或者穿刺才能了解患者的病理结果,而很多患者可能不具备获得病理标本的条件。CT作为诊断肺腺癌的首要方法,在肺腺癌新分类后,基于肺GGO的CT表现判断其能否为肿瘤组织病理学预测提供特征性指标,以期有助于GGO的确诊和指导临床治疗。

With the widespread use of muhi-slice spiral computed tomography(CT)and the increasing level of diagnosis and treatment,the incidence of pulmonary ground glass opacity(GGO)is inereasmg.The etiology of GGO is complex and the pathological types are diverse.In addition to benign lesions,GGO can be a specific type of lung adenocarcinoma or its invasive lesions.Some scholars think it is closely related to early lung adenocarcinoma.Histopathology of lung cancer is crucial for the prognosis and treatment of lung cancer.However,under normal circumstances,the pathology of the patient can be known by surgery,bronchoscopy or puncture.However,many patients may not have the pathological conditions for obtaining the pathological specimen.CT as the primary method of diagnosis of lung adenocarcinoma,lung adenocarcinoma in the new classification,based on the lung GGO CT findings to determine its ability to provide a characteristic indicator of tumor histopathology in order to help GGO diagnosis and guidance of clinical treatment.