黄体酮联合固肾安胎丸治疗先兆流产患者的临床效果观察

Clinical Observation of Progesterone Combined with Gushen Antai Pill in the Treatment of Threatened Abortion

目的研究先兆流产患者肌肉注射黄体酮联合口服固肾安胎丸治疗的临床效果。方法选取2015年1月～2017年12月我院的100例先兆流产患者,随机分为两组。对照组肌肉注射黄体酮治疗,每次20 mg,每天1次,观察组联合口服固肾安胎丸治疗,每次1袋,每天3次。比较两组临床治疗有效率,并检测两组治疗前后的血清β-HCG水平以及血清β-HCG恢复正常时间。结果观察组先兆流产患者显效26例,有效21例,无效3例,治疗有效率为94.00%(47/50),明显高于对照组的76.00%(38/50)(P<0.05);观察组血清β-HCG恢复正常时间明显短于对照组(P<0.05),治疗后两组的血清β-HCG水平均明显升高(P<0.05),且观察组的血清β-HCG水平明显高于对照组(P<0.05)。结论肌肉注射黄体酮联合口服固肾安胎丸治疗先兆流产患者的临床效果显著优于单纯肌肉注射黄体酮治疗,可以有效改善血清β-HCG水平。

Objective To study the clinical effect of intramuscular injection of progesterone combined with oral administration of Gushen Antai pill in patients with threatened abortion.Methods 100 cases of threatened abortion patients in our hospital from January 2015 to December 2017 were randomly divided into two groups. The control group was treated with intramuscular injection of progesterone (20 mg each time),once a day,while the observation group was treated with oral administration of Gushen Antai pill (1 bag each time),three times a day.The clinical treatment efficiency of patients with threatened abortion in the two groups was compared,and serum beta2-heg levels and normal recovery time of serum beta2-hcg before and after treatment in the two groups were measured.Results 26 cases of threatened abortion patients in the observation group showed significant effect,21 cases were effective,and 3 cases were ineffective.The effective rate of treatment was 94.00%(47/ 50),significantly higher than 76.00%(38/50)in the control group (P<0.05).The normal recovery time of serum betabcg in the observation group was significantly shorter than that in the control group (P<0.05),and serum betahcg levels in both groups were significantly inereased after treatment (P<0.05),and serum betahcg levels in the observation group were significantly higher than those in the control group (P<0.05).Conclusion The clinical effect of intramuscular progesterone injection combined with oral Gushen Antai pill in the treatment of patients with threatened abortion is significantly better than that of intramuscular progesterone injection alone,and can effectively improve serum betave-hcg level.