2013～2016年贵州省黔东南州健康人群乙型肝炎表面抗体水平调查

Analysis of the Monitoring results of HBsAb among healthy population in Qiandongnan prefecture of Guizhou in 2013～2016

目的:了解贵州省黔东南州健康人群乙型肝炎(乙肝)表面抗体水平,评价人群免疫现状,为制定乙肝防控策略提供依据。方法:按照分层随机抽样原则,收集2013～2016年健康人群血清标本,采用酶联免疫吸附(ELISA)法进行乙肝表面抗体(HBs Ab)检测,分析HBs Ab阳性率。结果:2073名调查者中HBs Ab阳性1201人,阳性率57. 94%。HBs Ab阳性率随年龄增高而降低(P <0. 01);男女HBs Ab阳性率无差异(P> 0. 05);不同地区HBs Ab阳性率有差异(P <0. 01);有接种史的人群HBs Ab阳性率高于无接种史的人群(P <0. 05)。结论:黔东南州健康人群HBs Ab水平较低,应抓好儿童乙肝疫苗的全程接种,提高乙肝疫苗首针及时接种率,加强查漏补种和适时开展强化免疫工作,提高人群免疫水平。

Objective: To understand the antibody level of hepatitis b surface in healthy people in Qiandongnan prefecture,that could evaluate the status of the population immunity. It can provide the basis for the prevention and control strategy of hepatitis B. Methods: According to the principle of stratified random sampling,the serum samples of healthy population were collected from 2013 to 2016 Years.HBsAb was detected by ELISA,and the positive rate of HBsAb was analyzed. Results: A total of2073 cases were detected,HBsAb of1201 cases were positive( 57. 94%). With the increasing of age,the positive rate of HBsAb decreased( P < 0. 01). There was no difference in HBsAb positive rate between male and female( P > 0. 05),The positive rate of HBsAb was significantly different in different regions( P < 0. 01),People with the history of inoculation HBsAb had higher positive rate than those without( P < 0. 05). Conclusion: The level of HBsAb among healthy population in Qiandongnan prefecture was low. In order to improve the vaccination rate of hepatitis B vaccine,that need to pay special attention to whole process basic immunization of the hepatitis B among children,and to increase the first dose coverage rate,and to strengthen leak checking and carrying out aggrandized immunization work.