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Phase separation—a strategy to resist autophagic degradation under heat stress

Phase separation—a strategy to resist autophagic degradation under heat stress
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摘要 Stress spans our whole lives. When exposed to stressful conditions, every life, from a worm to a human, adjusts its internal properties to adapt to new environments. This principle applies to adults, and is also essential during development in animals. Dr. Zhang and coworkers from Institute of Biophysics, Chinese Academy of Sciences made a remarkable discovery showing that heat-stress-triggered accumulation of PGL granules is an adaptive response to maintain embryonic viability (Figure 1). Their work was published in the September 6th issue of Cell, entitled"mTOR regulates phase separation of PGL granules to modulate their autophagic degradation"(Zhang et al., 2018).
作者 Wenyu Wen
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2019年第1期148-149,共2页 中国科学(生命科学英文版)
分类号 Q [生物学]
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