摘要
Stress spans our whole lives. When exposed to stressful conditions, every life, from a worm to a human, adjusts its internal properties to adapt to new environments. This principle applies to adults, and is also essential during development in animals. Dr. Zhang and coworkers from Institute of Biophysics, Chinese Academy of Sciences made a remarkable discovery showing that heat-stress-triggered accumulation of PGL granules is an adaptive response to maintain embryonic viability (Figure 1). Their work was published in the September 6th issue of Cell, entitled"mTOR regulates phase separation of PGL granules to modulate their autophagic degradation"(Zhang et al., 2018).