摘要
发展了一种简单、实用可见光诱导喹喔啉-2(1H)-酮与重氮盐的直接C—H 3-芳基化反应.该反应采用便宜Eosin Y为催化剂,可以在室温、空气下高效完成3-芳基喹喔啉-2(1H)-酮的构建.该方法不需要任何金属试剂、碱、酸和强氧化剂,为3-芳基喹喔啉-2(1H)-酮提供一个价格便宜、操作简便的合成方法.
A simple and practical visible-light-induced protocol has been developed for the construction of 3-arylquinoxalin-2(1H)-ones via Eosin Y-catalyzed direct C-H 3-arylation of quinoxalin-2(H)-ones with aryl diazonium salts at room temperature in air. The present reaction provides a cost-effective and operationally straightforward approach to the target products in moderate to good yields, and does not require any metal reagents, bases, acids, and strong oxidants.
作者
王雷雷
鲍鹏丽
刘维维
刘思彤
胡昌松
岳会兰
杨道山
魏伟
Wang Leilei;Bao Pengli;Liu Weiwei;Liu Sitong;Hu Changsong;Yue Huilan;Yang Daoshan;Wei Wei(School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165;Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology, Chinese Academy of Sciences,Xining 810008)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2018年第12期3189-3196,共8页
Chinese Journal of Organic Chemistry
基金
Supported by the Natural Science Foundation of Shandong Province(Nos.ZR2018MB009,ZR2016JL012)
the International Cooperation Project of Qinghai Province(Nos.2018-HZ-806,2017-HZ-806)
the National Natural Science Foundation of China(Nos.21302109,21302110)~~
