摘要
通过碘介导的氧化性C—O键形成反应由易得的α,β-不饱和肟合成了一系列单、双和三取代(芳基、烷基和/或烯基)的异噁唑类化合物.该合成方法具有不使用过渡金属、操作简单、反应条件温和、反应时间短,以及底物适用范围广等优点.
A variety of mono-, di-, and tri-substituted(aryl, alkyl, and/or alkenyl) isoxazoles were synthesized from readily accessible α,β-unsaturated oximes via I2-mediated oxidative C-O bond formation. The features of this synthetic approach include no use of transition metals, simple operation, mild reaction conditions, short reaction time, and broad substrate scope.
作者
侯姣
张新婷
于文全
常俊标
Hou Jiao;Zhang Xinting;Yu Wenquan;Chang Junbiao(College of Chemistry and Molecular Engineering,Zhengzhou University,Zhengzhou 450001)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2018年第12期3236-3241,共6页
Chinese Journal of Organic Chemistry
基金
supported by the National Natural Science Foundation of China(Nos.81773570,81330075)
the Outstanding Young Talent Research Fund of Zhengzhou University(No.1521316004)~~
