算盘七化学成分及药理作用研究进展

Research progress on chemical constituents and pharmacological activities of pseudo phosphorous stem of Cremastra appendiculata

算盘七(杜鹃兰Cremastra appendiculata的假鳞茎)是具有地区特色的陕西七药之一,作为临床抗肿瘤药材,近年来关注度一直较高。算盘七主要含菲类、二氢菲类、联苄类、黄酮类、萜类、生物碱等化学成分,具有抗肿瘤、抗菌、抗血管生成、降压等药理活性。系统综述了算盘七化学成分和药理作用的研究进展,以期为研究其药效物质基础提供科学的依据,从而进一步促进地区特色植物资源的开发利用。

Pseudo phosphorous stem of Cremastra appendiculata(Suanpanqi) is one of Shaanxi Qiyao with regional characteristics. As a clinical antitumor drug, it has been highly concerned in recent years. Suanpanqi mainly contains phenanthrene, dihydrophenanthrene, bibenzyl, flavonoids, terpenes, alkaloids, and other chemical components with antitumor, antibacterial, anti-angiogenic, antihypertensive, and other pharmacological activities. This paper systematically reviews the research progress on the chemical composition and pharmacological effects of Suanpanqi at home and abroad in order to provide a scientific basis of its efficitive material basis, so as to further promote the value of development and utilization of plant resources in China.