中西医结合治疗老年急性梗阻性化脓性胆管炎临床观察

Effect of Traditional Chinese Medicine Combined with Western Medicine in Treatment of Elderly Patients with Acute Obstructive Suppurative Cholangitis

目的:分析中西医结合治疗老年急性梗阻性化脓性胆管炎的效果。方法:98例老年急性梗阻性化脓性胆管炎患者,按随机数字表法分为两组:观察组和对照组。对照组49例患者给予常规西医治疗,观察组49例患者在对照组的基础上给予中医治疗。对比两组的血清丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、血清总胆红素、血清直接胆红素以及相关观察指标。结果:治疗后,观察组患者的血清丙氨酸氨基转移酶(44.08±15.70)U/L、天门冬氨酸氨基转移酶(39.65±11.30)U/L、血清总胆红素(26.08±7.23)μmol/L、血清直接胆红素(14.65±2.80)μmol/L以及腹膜炎发生率、肾功能衰竭发生率、肺部感染发生率、血淀粉酶升高率、死亡率较对照组患者的血清丙氨酸氨基转移酶(67.40±15.40)U/L、天门冬氨酸氨基转移酶(39.65±11.30)U/L、血清总胆红素(66.20±10.40)μmol/L、血清直接胆红素(32.23±7.50)μmol/L以及腹膜炎发生率、肾功能衰竭发生率、肺部感染发生率、血淀粉酶升高率、死亡率明显降低,差异具有统计学意义(P<0.05)。结论:老年急性梗阻性化脓性胆管炎中西医结合治疗的效果显著,能够有效降低患者天门冬氨酸氨基转移酶、血清总胆红素等相关指标水平,改善患者预后水平。

Objective: To analyze the effect of traditional Chinese medicine combined with Western medicine treatment of elderly patients with acute obstructive suppurative cholangitis.Methods: 98 cases of elderly patients with acute obstructive suppurative cholangitis were randomly divided into two groups: the observation group and the control group.Forty-nine patients of the control group were given conventional Western medicine treatment, and the other 49 patients of the observation group on the basis of the control group were given traditional Chinese medicine treatment.The serum alanine aminotransferase, aspartate aminotransferase, serum total bilirubin, serum direct bilirubin and the related observation indexes were compared between two groups.Results: After treatment, the observatin group's serum alanine amino transferase(44.08±15.70)U/L, aspartate aminotransferase(39.65±11.30)U/L, serum total bilirubin(26.08±7.23)mol/L, serum direct bilirubin(14.65±2.80)mol/L, peritonitis incidence, renal failure, the incidence of pulmonary infection, blood amylase and mortality rate were significantly decreased than those of the control group[serum alanine amino transferase(67.40±15.40)U/L, aspartate aminotransferase(39.65±11.30)U/L, serum total bilirubin(66.20±10.40)mol/L, serum direct bilirubin(32.23±7.50)mol/L, the incidence of peritonitis, renal failure, the incidence rate of pulmonary infection, blood amylase and mortality rate], and the difference was statistically significant(P<0.05).Conclusion: Traditional Chinese medicine combined with Western medicine treatment has significant effect on elderly patients with acute obstructive suppurative cholangitis and can effectively reduce the patients' aspartate aminotransferase, serum total bilirubin levels and other related indicators and improve the prognosis of patients.