2013—2016年北京地区孕妇维生素A、维生素E营养水平

Trend of vitamin A and vitamin E among pregnancy of Beijing in 2013—2016

目的分析和描述2013—2016年北京地区孕妇维生素A和维生素E营养水平。方法选取2013年1月—2016年12月北京地区18～47岁孕妇首次到医院就诊同时检测维生素A、维生素E血清样本5487例,采用高效液相色谱法定量测定血清维生素A、维生素E的浓度,并与正常人群血清维生素A、维生素E的浓度作比较。定性分析2013—2016年4年间孕妇维生素A、维生素E营养状况变化趋势及改善状况。结果 2013—2016年间,北京地区孕妇血清维生素A的检测值[以中位数(四分位数间距)表示]分别为1.23 (1.05～1.44)、1.40 (1.19～1.68)、1.51 (1.30～1.75)和1.54 (1.30～1.79)μmol/L,总体异常率4年分别为22.3%、14.6%、8.1%和8.6%,以缺乏为主要表现(21.6%、13.4%、6.8%和6.4%);血清维生素E的检测值[以中位数(四分位数间距)表示]分别为36.00 (28.80～45.00)、30.72 (25.44～37.92)、30.00 (24.96～35.52)和31.68 (26.40～37.92)μmol/L,总体异常率4年分别为17.4%、7.5%、3.6%和4.3%,以过量为主要表现(17.4%、7.5%、3.6%和4.0%)。结论 2013—2016年北京地区孕妇血清维生素A水平呈逐年上升趋势,血清维生素E水平呈先下降后上升的趋势。维生素A、维生素E整体营养状况有所改善。

OBJECTIVE To describe the nutrition level of vitamin A and vitamin E among pregnancy of Beijing and the trends from 2013 to 2016.METHODS A total of 5487 serum samples from pregnant women who simultaneous detection for the first time from January 2013 to December 2016 in Beijing were enrolled in the study,then high performance liquid chromatography (HPLC)method was used to determine the concentration of serum vitamin A and vitamin E,and it was compared with serum concentrations of vitamin A,vitamin E in normal people.Qualitative analysis of the trend of vitamin A and vitamin E nutrition in pregnant women from 2013 to 2016.RESULTS From 2013 to 2016,the serum concentration of vitamin A (median (four guantile sapeing))was 1.23 (1.05-1.44),1.40 (1.19-1.68),1.51 (1.30-1.75)and 1.54 (1.30-1.79)Nmol/L,respectively.The total abnormal rate for four years running was 22.3%,14.6%,8.1%and 8.6%,respectively,with main performance of lacking (21.6%,13.4%,6.8% and 6.4%,respectively).The serum concentration of vitamin E (median (four guantile sapeing))was 36.00 (28.80-45.00),30.72 (25.44-37.92), 30.00 (24.96 -35.52)and 31.68 (26.40 -37.92)μmol/L,respectively.The total abnormal rate from 2013 to 2016 was 17.4%,7.5%,3.6%and 4.3%,respectively, with excess (17.4%,7.5%,3.6% and 4.0%,respectively)as the main performance. CONCLUSION For the pregnancy of Beijing between 2013 and 2016,the nutrition level of vitamin A showed an increasing trend and serum vitamin E level showed a tendency to decrease first and then rise.The overall nutritional status of vitamin A and vitamin E had improved.