成都地区脑性瘫痪患儿422例伴发小头畸形临床分析

Clinical analysis of children with cerebral palsy complicated by microcephaly in Chengdu

目的分析伴小头畸形脑性瘫痪(脑瘫)患儿的临床特征,为合理康复管理提供依据。方法总结2013年2月至4月对成都市辖区残联登记为脑性瘫痪的0～18岁儿童进行了横断面调查结果,共计422例。根据头围对患儿进行分组,分析脑瘫患儿头围与粗大运动功能损伤程度(GMFCS)、智力、合并症等相关性。结果两组不同程度头围组与GMFCS分级的分布情况差异有统计学意义(P=0.001)、两组不同程度头围组与认知分级分布情况差异有统计学意义(P<0.001),Spearman相关分析示伴小头畸形脑瘫患儿的伴发障碍数量、GMFCS和认知损伤程度与头围呈负相关(P<0.001)。结论伴小头畸形的脑瘫患儿头围减小程度与GMFCS、伴发障碍的数量和认知损伤程度呈负相关。

Objective(CP);to provide evidence for rehabilitation management. Methods To summarize the results of a cross-sectional survey of a total of 422 children(0-18 years old)who were registered as cerebral palsy by Disabled Persons’ Federation of Chengdu from February to April in 2013. All children were grouped according to head circumference. We analyzed the correlation between head circumference with gross motor function classification system(GMFCS),intelligence and complications. Results There were statistically significant between the two different degrees of head circumference group and the classification of GMFCS and cognition respectively(P<0.001). Spearman correlation analysis showed that the number of comorbidities,GMFCS and degree of cognitive damage in children with cerebral palsy with microcephaly were negatively correlated with head circumference(P<0.001). Conclusion The degree of head circumference reduction in children with cerebral palsy complicated by microcephaly is negatively correlated with GMFCS,the number of comorbidities and the degree of cognitive impairment.