胰高血糖素瘤综合征1例

A Case of Glucagonoma Syndrome

患者男,44岁。躯干、四肢出现红斑、糜烂伴痒4个月,加重1个月。皮损组织病理示:角化过度伴融合性角化不全,棘层增生肥厚,皮突下延增宽,可见部分棘层上部细胞胞浆空泡化和苍白,真皮浅层淋巴组织细胞浸润。诊断:胰高血糖素瘤综合征。

A 44-year-old male presented with recurrent erythema and erosion accompanied by itchiness for four months,which were aggravated for one month.The histopathologic examination showed epidermal hyperkeratosis with confluent parakeratosis,acanthosis,elongation of the rete ridges,partial vacuolated and pale staining cells and a few necrotic cells in the upper part of the epidermis,and mild lymphohistiocytic infiltration in the superficial dermis.A diagnosis of glucagonoma syndrome was established.