呼吸道病原体九联检在小儿急性呼吸道疾病中的应用

Application of respiratory pathogens nine-joint inspection in children with acute respiratory disease

目的探讨呼吸道病原体九联检在小儿急性呼吸道疾病诊断中的应用价值。方法选取2015年1月—2016年5月福建医科大学附属宁德市医院收治的1 080例急性呼吸道疾病患儿作为研究对象,采用呼吸道病原体九联检法检测所有患儿的血清标本,观察患儿的检测和诊断结果并进行分析。结果呼吸道病原体九联检法检测结果显示,1 080例小儿急性呼吸道疾病患儿中,有呼吸道症状且病原体检测阳性患儿460例,阳性率42.59%。其中嗜肺军团菌血清1型4例(0.37%),肺炎衣原体0例(0%),腺病毒14例(1.30%),肺炎支原体172例(15.93%),呼吸道合胞病毒53例(4.90%),Q热立克次体0例(0%),甲型流感病毒0例(0%),副流感病毒47例(4.35%),乙型流感病毒170例(15.74%)。结论呼吸道病原体九联检法能及早确定患儿的感染病因,促进患儿的后续治疗,值得推广应用。

Objective To explore the application value of the combined examination of respiratory pathogens in the diagnosis of children with acute respiratory diseases. Methods One thousand and eighty children with acute respiratory diseases admitted into Ningde City Hospital Affiliated to Fujian Medical University from January 2015 to May 2016 were selected as study subjects. All serum specimens of all children were tested by the nine joint inspections of respiratory pathogens, and the results of detection and diagnosis were observed and analyzed. Results The results of nine-joint inspection for detection of respiratory pathogens showed: in 1 080 children with acute respiratory diseases, there were 460 cases with respiratory symptoms and positive pathogen detection, the rate of positivity being 42.59%. There were 4 cases with Eosinophilic lung legionella serum type 1(0.37%), Pneumonia chlamydia 0 case(0%), Adenovirus 14 cases(1.30%), Mycoplasma pneumoniae 172 cases(15.93%), Respiratory syncytial virus 53 cases(4.90%), Q fever rickettsia 0 case(0%), Influenza A virus 0 case(0%), Parainfluenza 47 cases(4.35%), and Influenza B virus 170 cases(15.74%). Conclusion The application of nine-joint detection of respiratory pathogens in children with acute respiratory diseases can determine the causes of infection as early as possible, promote the further proper treatment, and is worthy to be popularized and applied.