五苓散加减联合常规西药治疗慢性心力衰竭临床研究

Clinical Study on Modified Wuling Powder Combined with Routine Western Medicine for Chronic Heart Failure

目的:观察五苓散加减联合常规西药治疗慢性心力衰竭的临床疗效。方法:选取80例慢性心力衰竭患者为研究对象,随机分为对照组和治疗组各40例。对照组予常规西药治疗,治疗组在对照组基础上加用五苓散加减。对比2组临床疗效,观察2组治疗前后左心室射血分数(LVEF)及24 h尿量的变化。结果:治疗组总有效率95.0%,对照组总有效率82.5%,2组比较,差异有统计学意义(P <0.05)。治疗前,2组LVEF及24 h尿量比较,差异均无统计学意义(P> 0.05)。治疗后,2组LVEF均较治疗前提升,24 h尿量均较治疗前增加,差异均有统计学意义(P <0.05);治疗组LVEF高于对照组,24 h尿量多于对照组,差异均有统计学意义(P <0.05)。结论:五苓散加减联合常规西药治疗慢性心力衰竭,可有效改善患者的心功能,提高临床疗效。

Objective:To observe the clinical effect of modified Wuling powder combined with routine western medicine for chronic heart failure. Methods:Selected 80 cases of patients with chronic heart failure as study subjects, and divided them into the control group and the treatment group randomly,40 cases in each group. The control group received routine western medicine for treatment,while the treatment group received modified Wuling powder based on the treatment of the control group. Compared the clinical effect and observed the changes in left ventricular ejection fraction(LVEF) and 24 h urine volume before and after treatment in the two groups. Results:The total effective rate was 95.0% in the treatment group and82.5% in the control group,the difference being significant(P < 0.05). Before treatment,compared with LVEF and 24 h urine volume in the two groups,there was no significance in the differences(P > 0.05). After treatment,LVEF in the two groups were improved when compared with those before treatment,24 h urine volume were increased when compared with those before treatment, differences being significant(P < 0.05). LVEF in the treatment group was higher than that in the control group,24 h urine volume in the treatment group was more than that in the control group,differences being significant(P < 0.05).Conclusion:The therapy of modified Wuling powder combined with routine western medicine for chronic heart failure can improve the heart function of patients and improve the clinical effect.