重视儿童“侧呼吸道”过敏性炎症

Paying attention to the 'lateral airway' allergic diseases in children

过敏性疾病是全身多器官的系统性疾病,随年龄增长存在"过敏进程",具有外在的多种表型,也存在内在的紧密联系,又因年龄和人群的差异而变化多端。由于儿童存在身体结构和免疫系统的动态变化而比较特殊,因此聚焦"儿童""呼吸道""过敏性疾病"显得尤为重要。过敏性鼻炎、过敏性哮喘和分泌性中耳炎是三种来自同一气道、不同解剖部位的儿童呼吸道疾病,其关联性越来越受到关注,涉及上、下和侧呼吸道过敏性炎症是否存在一致性值得深入探讨,通过临床研究和循证医学证据提出我们的思考。

Allergic diseases are autoimmune diseases that involve multi-organ systems producing a variety of clinical manifestations;concurrently,there is an intrinsic and inseparable link between multiple systems and clinical manifestations,producing a variety of manifestations among different age-groups and populations. Focusing on allergic diseases that are associated with the respiratory airway in children is relatively complicated due to the dynamic changes observed with respect to their body structures and immune systems.Allergic rhinitis,allergic asthma,and otitis media with effusion are three examples of allergic respiratory diseases in children that affect the same airway at different anatomical regions,and the correlation between them is receiving greater attention. Whether the upper,lower,and lateral airways could ever truly be in concurrence with each other is worth an in-depth discussion,and thus,we put forward some minor thoughts and suggestions based on the available clinical research and literature.