围手术期质子泵抑制剂应用的合理性评价

Evaluation of the application of proton pump inhibitors in perioperative period

目的分析浙江省舟山医院围手术期质子泵抑制剂的使用情况,为临床制定出适宜的质子泵抑制剂临床应用管理规定。方法统计舟山医院2016年9-10月围手术期患者使用质子泵抑制剂的情况,对其适应证、用药品种、给药方式、给药剂量、给药时间、疗程、合并用药等进行合理性评价。结果614份病例中不合理使用质子泵抑制剂273份,不合格率为44.46%(273/614),主要表现在无指征用药和用药疗程过长。结论质子泵抑制剂在临床使用过程中存在许多不合理现象,医生及临床药师应进一步加强监督和管理质子泵抑制剂的使用。

Objective ,To analyze the use of proton pump inhibitors (PPIs)in the perioperative period of Zhoushan Hospital,thus to make appropriate management regulations for the clinical application of PPIs.Methods From September 2016 to October 2016,the use of PPIs in 614 surgical patients of Zhoushan Hospital were statistically analyzed.The rationality of the indications,drug use,drug administration,dosage,time,course of treatment,combined medication were analyzed.Results In 614 cases,there were 341 reasonable,unreasonable 273,the failure rate was 44.46%(273/614).The main manifestations in the non indication of medication and medication course of treatment was too long.Conclusion There are many unreasonable phenomena in the course of clinical use of PPIs.Hospital and clinical pharmacists should strengthen supervision and management of the use of PPIs.