心房颤动患者的脑卒中预防

Stroke prevention in atrial fibrillation

脑卒中是全球第二大死亡原因,心房颤动是最常见的持续性心律失常,也是脑卒中的独立风险因素。心房颤动患者的脑卒中主要累及大动脉,复发及致残率高,因此该人群脑卒中的预防至关重要。抗凝治疗可以显著降低心房颤动患者缺血性脑卒中风险。现就心房颤动患者脑卒中的流行病学特征以及脑卒中预防中的心房颤动探测、风险评估、抗凝及其他预防手段等方面的新进展进行综述,为临床实践提供参考。目前,心房颤动患者的脑卒中预防工作仍需推广落实,更为精确便捷的风险评估模型以及价廉效佳、安全性高的缺血性脑卒中预防手段也有待进一步研究。

Stroke is the second leading cause of death worldwide. Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an independent risk factor for stroke.AF-caused stroke has a high risk of recurrence and disability, mainly involving large cerebral artery.Thus, stroke prevention in AF becomes a major health priority. Anticoagulant therapy can significantly reduce the risk of ischemic stroke in patients with AF.This review summarized the epidemiological status of AF-related stroke, and reported updated information on AF detection, risk assessment, anticoagulation as well as other preventive measures in stroke prevention in AF, in order to provide theoretical references for clinical practice. At present, the prevention of AF-related stroke still needs to be promoted. Better risk assessment model, as well as cost-effective and safe ischemic stroke prevention methods, are still need to be further studied.