延边地区PM2.5水平与冠心病发病的关系

Relationship between the levels of PM2.5 and the incidence of coronary heart disease in Yanbian area

[背景]探讨延边地区PM2.5水平与冠心病发病的关系.[病例报告]选择2010年1月—2017年12月间诊断为冠心病的患者4 673例,分为2010年1月—2013年12月和2014年1月—2017年12月两组,比较上述2个时间段间的气象因素和PM2.5水平,同时比较两组冠心病发病情况,并进行相关分析.结果见,上述2个时间段春、夏、秋、冬PM2.5水平间差异有统计学意义(P<0.05,P<0.01),两组冠心病发病人数间差异亦有统计学意义(P<0.05,P<0.01),而2个时间段气象条件中气温、气压间无明显差异(P>0.05);PM2.5水平与冠心病有相关性(r=0.386 5,P<0.05).[讨论]PM2.5水平升高可增高冠心病发病率.

BACKGROUND To explore the relationship between the levels of PM2.5 and the incidence of coronary heart disease in Yanbian area.CASE REPORTS 4 673 patients diagnosed with coronary heart disease between January 2010 and December 2017 were collected,and they were divided into two groups,January 2010 to December 2013 and January 2014 to December 2017.Meteorological factors and PM2.5 levels in the above periods were compared,meanwhile the incidence of coronary heart disease was compared between the two groups.The correlation analysis was carried out.The results showed that there were statistically significant differences in the PM2.5 levels of the spring,summer,autumn and winter between the above two periods(P<0.05,P<0.01),and there was also a statistically significant difference in the number of coronary heart disease between the two groups(P <0.05,P <0.01),while there was no significant difference in temperature and pressure between the two periods(P>0.05).PM2.5 levels were associated with coronary heart disease(r=0.386 5,P<0.05).DISCUSSION The levels of PM2.5could increase the incidence of coronary heart disease.